MolNFT v1 · #183541 · protein + DNA
X-ray structure of the complex between human alpha thrombin and two DUPLEX/QUADRUPLEX aptamers: NU172 and HD22_27MER
7NTU: “X-ray structure of the complex between human alpha thrombin and two DUPLEX/QUADRUPLEX aptamers: NU172 and…”. X-ray diffraction, 2 ligands (NAG, NA). MolNFT v1 #183541 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7NTU
- Type
- protein + DNA
- Length
- 662 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00734
- Ligands
- NAG, NA
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | — | protein | 28 | — | P00734 |
| B, D | — | protein | 250 | — | P00734 |
| E, G | — | dna | 26 | — | — |
| F, I | — | dna | 27 | — | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains B, D
- NA · Sodium ion · metal · 4 copies · chains E, F, G, I
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7NTU · X-ray structure of the complex between human alpha thrombin and two duplex/quadruplex… · the same entry in another collection · chain I against I, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00734
- Elsewhere: RCSB PDB 7NTU · PDBe 7NTU · UniProt P00734
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