MolNFT v1 · #183527 · protein

The structure of an open conformation of the sbp TARP_CSAL

7NTE · Trap dicarboxylate transporter-dctp subunit: “The structure of an open conformation of the sbp TARP_CSAL”. X-ray diffraction, 1 ligand (MG), 3 pockets (best druggability 0.87). MolNFT v1 #183527 on GenesisL1: 3D structure, binding…

PDB: 7NTE
Type: protein
Length: 654 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Trap dicarboxylate transporter-dctp subunit
UniProt: Q1R0W5
Ligands: MG
Pockets: 3 · best druggability 0.87

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Trap dicarboxylate transporter-dctp subunit	protein	327	48% helix, 16% strand	Q1R0W5

Ligands and binding sites

MG · Magnesium ion · metal · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	930	0.87	0.88	120	empty
2	211	0.54	0.78	22	empty
3	195	0.51	0.77	22	empty

Interfaces

1 interface between chains.

A–B · 796 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

7NTE · The structure of an open conformation of the SBP TarP_Csal · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1R0W5
Elsewhere: RCSB PDB 7NTE · PDBe 7NTE · UniProt Q1R0W5

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