MolNFT v1 · #183448 · protein
C-terminal bromodomain of human BRD2 with N-ethyl-3-(1-methyl-1H-1,2, 3-triazol-4-yl)-4-(pyridin-2-YLMETHOXY)BENZAMIDE
7NQ8: “C-terminal bromodomain of human BRD2 with N-ethyl-3-(1-methyl-1H-1,2…”. X-ray diffraction, 1 ligand (UM5). MolNFT v1 #183448 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7NQ8
- Type
- protein
- Length
- 111 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P25440
- Ligands
- UM5
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 111 | — | P25440 |
Ligands and binding sites
- UM5 · N-ethyl-3-(1-methyl-1H-1,2,3-triazol-4-yl)-4-(pyridin-2-ylmethoxy)benzamide · ligand · chains A
- EDO · 1,2-ethanediol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7NQ8 · C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-ethyl-3-(1-methyl-1H-1,2,3-triazol-4-yl)-4-(py… · the same entry in another collection · chain A against A, TM-score 1.00
- P25440 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 2 (P25440) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25440
- Elsewhere: RCSB PDB 7NQ8 · PDBe 7NQ8 · UniProt P25440
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