MolNFT v1 · #183333 · protein
Solution structure of mlkl executioner domain in complex with a fragment
7NM2 · Mixed lineage kinase domain-like protein: “Solution structure of mlkl executioner domain in complex with a fragment”. Solution nmr, 1 ligand (UJ5), 1 pocket (best druggability 0.58). MolNFT v1 #183333 on GenesisL1: 3D structure…
- PDB
- 7NM2
- Type
- protein
- Length
- 157 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mixed lineage kinase domain-like protein
- UniProt
- Q8NB16
- Ligands
- UJ5
- Pockets
- 1 · best druggability 0.58
Structure
solution nmr · 1 distinct chain · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mixed lineage kinase domain-like protein | protein | 157 | 70% helix, 0% strand | Q8NB16 |
Ligands and binding sites
- UJ5 · 2-[(~{S})-methoxy-(4-propan-2-ylphenyl)methyl]-3~{H}-benzimidazole-5-carboxylic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 109 | 0.58 | 0.85 | 21 | UJ5 |
Compared structures
- 7NM2 · Solution structure of MLKL executioner domain in complex with a fragment · the same entry in another collection · chain A against A, TM-score 1.00
- Q8NB16 · AlphaFold monomer V2.0 prediction for mixed lineage kinase domain- like protein (Q8NB16) · a predicted model of the same protein · chain A against A, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NB16
- Elsewhere: RCSB PDB 7NM2 · PDBe 7NM2 · UniProt Q8NB16
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.