MolNFT v1 · #183016 · protein
Glutathione-S-transferase glig mutant H26A
7NCB · Glutathione S-transferase glig: “Glutathione-S-transferase glig mutant H26A”. X-ray diffraction, 6 pockets (best druggability 0.73). MolNFT v1 #183016 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7NCB
- Type
- protein
- Length
- 478 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutathione S-transferase glig
- UniProt
- B0Y813
- Pockets
- 6 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutathione S-transferase glig | protein | 238 | 50% helix, 9% strand | B0Y813 |
| B | Glutathione S-transferase glig | protein | 240 | 50% helix, 9% strand | B0Y813 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 524 | 0.73 | 0.81 | 51 | empty |
| 2 | 509 | 0.73 | 0.82 | 50 | empty |
| 3 | 286 | 0.66 | 0.83 | 25 | empty |
| 4 | 142 | 0.39 | 0.73 | 22 | empty |
| 5 | 113 | 0.34 | 0.73 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 2186 Ų buried · 42 hydrogen bonds · protein-protein
Compared structures
- 7NCB · Glutathione-S-transferase GliG mutant H26A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B0Y813
- Elsewhere: RCSB PDB 7NCB · PDBe 7NCB · UniProt B0Y813
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