MolNFT v1 · #182967 · protein
Crystal structure of escherichia COLI dihydrofolate reductase in complex with trimethoprim
7NAE: “Crystal structure of escherichia COLI dihydrofolate reductase in complex with trimethoprim”. X-ray diffraction, 2 ligands (TOP, SO4). MolNFT v1 #182967 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7NAE
- Type
- protein
- Length
- 159 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0ABQ4
- Ligands
- TOP, SO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 159 | — | P0ABQ4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7NAE · Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM · the same entry in another collection · chain A against A, TM-score 1.00
- P0ABQ4 · AlphaFold monomer V2.0 prediction for dihydrofolate reductase (P0ABQ4) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0ABQ4
- Elsewhere: RCSB PDB 7NAE · PDBe 7NAE · UniProt P0ABQ4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.