MolNFT v1 · #182866 · protein

Mouse norovirus (mnv-1) capsid at pH 5.0

7N6Y · Capsid protein: “Mouse norovirus (mnv-1) capsid at pH 5.0”. Electron microscopy, 8 pockets (best druggability 0.64). MolNFT v1 #182866 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7N6Y
Type: protein
Length: 1,533 residues
Chains: 3
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Capsid protein
UniProt: Q80J94
Pockets: 8 · best druggability 0.64

Structure

electron microscopy · 3 distinct chains · 3% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Capsid protein	protein	513	4% helix, 30% strand	Q80J94
B	Capsid protein	protein	516	3% helix, 28% strand	Q80J94
C	Capsid protein	protein	504	3% helix, 29% strand	Q80J94

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	447	0.64	0.77	56	empty
2	261	0.62	0.81	39	empty
3	267	0.58	0.78	39	empty
4	112	0.42	0.77	22	empty
5	82	0.39	0.78	19	empty

Interfaces

3 interfaces between chains.

A–C · 1225 Å² buried · 12 hydrogen bonds · protein-protein
A–B · 914 Å² buried · 9 hydrogen bonds · protein-protein
B–C · 849 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

7N6Y · Mouse norovirus (MNV-1) capsid at pH 5.0 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q80J94
Elsewhere: RCSB PDB 7N6Y · PDBe 7N6Y · UniProt Q80J94

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