MolNFT v1 · #182703 · protein

SARS-cov-2 ylq peptide-specific TCR PYLQ7

7N1D · PYLQ7 T cell receptor alpha chain: “SARS-cov-2 ylq peptide-specific TCR PYLQ7”. X-ray diffraction, 4 pockets (best druggability 0.74). MolNFT v1 #182703 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7N1D
Type: protein
Length: 439 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PYLQ7 T cell receptor alpha chain; PYLQ7 T cell receptor beta chain
Pockets: 4 · best druggability 0.74

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PYLQ7 T cell receptor alpha chain	protein	199	3% helix, 47% strand	—
B	PYLQ7 T cell receptor beta chain	protein	240	8% helix, 50% strand	—

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1122	0.74	0.77	88	empty
2	77	0.38	0.78	22	empty
3	51	0.33	0.78	17	empty
4	64	0.29	0.74	19	empty

Interfaces

1 interface between chains.

A–B · 2127 Å² buried · 33 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

7N1D · SARS-CoV-2 YLQ peptide-specific TCR pYLQ7 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7N1D · PDBe 7N1D

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