MolNFT v1 · #182592 · protein

Crystal structure of the S/T protein kinase pkng from corynebacterium glutamicum (residues 130-433) in complex with AMP-pnp, isoform 2

7MXK · SERINE/THREONINE protein kinases: “Crystal structure of the S/T protein kinase pkng from corynebacterium glutamicum (residues 130-433) in…”. X-ray diffraction, 2 ligands (MAP, MG), 4 pockets (best druggability 0.70). MolNFT v1…

PDB: 7MXK
Type: protein
Length: 292 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SERINE/THREONINE protein kinases
UniProt: Q8NM29
Ligands: MAP, MG
Pockets: 4 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE protein kinases	protein	292	36% helix, 22% strand	Q8NM29

Ligands and binding sites

MAP · Magnesium-5'-adenyly-imido-triphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	521	0.70	0.80	56	MG, MAP
2	145	0.47	0.77	22	empty
3	54	0.31	0.76	18	empty
4	53	0.28	0.74	14	empty

Compared structures

7MXK · Crystal structure of the S/T protein kinase PknG from Corynebacterium glutamicum… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8NM29
Elsewhere: RCSB PDB 7MXK · PDBe 7MXK · UniProt Q8NM29

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