MolNFT v1 · #182573 · protein

Structure of the drosophila sting cyclic dinucleotide binding domain

7MWY: “Structure of the drosophila sting cyclic dinucleotide binding domain”. X-ray diffraction, 2 pockets (best druggability 0.71). MolNFT v1 #182573 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7MWY
Type: protein
Length: 352 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sting
Pockets: 2 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sting	protein	352	51% helix, 17% strand	—

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	752	0.71	0.77	73	empty
2	65	0.51	0.85	15	empty

Compared structures

7MWY · Structure of the drosophila STING cyclic dinucleotide binding domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7MWY · PDBe 7MWY

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