MolNFT v1 · #182567 · protein
Crystal structure of tamarin CD81 large extracellular loop
7MWS · CD81 protein: “Crystal structure of tamarin CD81 large extracellular loop”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #182567 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7MWS
- Type
- protein
- Length
- 193 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CD81 protein
- UniProt
- Q9N0J9
- Pockets
- 1 · best druggability 0.37
Structure
x-ray diffraction · 2 distinct chains · 63% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CD81 protein | protein | 96 | 66% helix, 0% strand | Q9N0J9 |
| B | CD81 protein | protein | 97 | 60% helix, 2% strand | Q9N0J9 |
Ligands and binding sites
- PG4 · Tetraethylene glycol · additive · 2 copies · chains A, B
- GOL · Glycerol · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.37 | 0.79 | 12 | PG4 |
Interfaces
1 interface between chains.
- A–B · 987 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9N0J9
- Elsewhere: RCSB PDB 7MWS · PDBe 7MWS · UniProt Q9N0J9
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