Structure of the minimally glycosylated human CEACAM1 N-terminal domain

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 51% strand (DSSP).

Ligands and binding sites

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A, B
• SO4 · Sulfate ion · ion · chains A
• GOL · Glycerol · additive · 10 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 845 Ų buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 glycan (N-glycosylation).

Compared structures

• 7MU8 · Structure of the minimally glycosylated human CEACAM1 N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
• P13688 · AlphaFold monomer V2.0 prediction for carcinoembryonic antigen- related cell adhesion… · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P13688
• Elsewhere: RCSB PDB 7MU8 · PDBe 7MU8 · UniProt P13688