MolNFT v1 · #182145 · protein
Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, model 5
7MI8 · Fusion protein of dynein and endolysin: “Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a…”. Electron microscopy, 13 pockets (best druggability 0.74). MolNFT v1 #182145 on GenesisL1: 3D…
- PDB
- 7MI8
- Type
- protein
- Length
- 868 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fusion protein of dynein and endolysin
- UniProt
- P36022
- Pockets
- 13 · best druggability 0.74
Structure
electron microscopy · 1 distinct chain · 56% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fusion protein of dynein and endolysin | protein | 868 | 56% helix, 10% strand | P36022 |
Pockets
13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1128 | 0.74 | 0.77 | 89 | empty |
| 2 | 188 | 0.68 | 0.86 | 30 | empty |
| 3 | 394 | 0.63 | 0.78 | 49 | empty |
| 4 | 186 | 0.56 | 0.80 | 26 | empty |
| 5 | 137 | 0.54 | 0.81 | 21 | empty |
Compared structures
- 7MI8 · Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P36022
- Elsewhere: RCSB PDB 7MI8 · PDBe 7MI8 · UniProt P36022
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