MolNFT v1 · #182069 · protein

The crystal structure of Q108K:K40L:T51V:T53S:R58W:Y19W:A33W:L117E mutant of hcrbpii bound with lizfluor

7MFY · Retinol-binding protein 2: “The crystal structure of Q108K:K40L:T51V:T53S:R58W:Y19W:A33W:L117E mutant of hcrbpii bound with lizfluor”. X-ray diffraction, 1 ligand (ZFG), 1 pocket (best druggability 0.83). MolNFT v1 #182069 on…

PDB: 7MFY
Type: protein
Length: 133 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Retinol-binding protein 2
UniProt: P50120
Ligands: ZFG
Pockets: 1 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Retinol-binding protein 2	protein	133	14% helix, 57% strand	P50120

Ligands and binding sites

ZFG · 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline · ligand · chains A
GOL · Glycerol · additive · 3 copies · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	178	0.83	0.98	31	ACT, ZFG

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

7MFY · The Crystal Structure of Q108K:K40L:T51V:T53S:R58W:Y19W:A33W:L117E Mutant of HCRBPII… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P50120
Elsewhere: RCSB PDB 7MFY · PDBe 7MFY · UniProt P50120

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