MolNFT v1 · #181983 · protein + DNA

Cryo-electron microscopy structure of TNSC(1-503)A225V bound to DNA

7MCS: “Cryo-electron microscopy structure of TNSC(1-503)A225V bound to DNA”. Electron microscopy, 2 ligands (ANP, MG). MolNFT v1 #181983 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7MCS
Type: protein + DNA
Length: 2,649 residues
Chains: 9
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P05846
Ligands: ANP, MG

Structure

electron microscopy · 9 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	249	—	P05846
B	—	protein	402	—	P05846
C	—	protein	404	—	P05846
D	—	protein	403	—	P05846
E	—	protein	402	—	P05846
F	—	protein	401	—	P05846
G	—	protein	358	—	P05846
H	—	dna	15	—	—
I	—	dna	15	—	—

Ligands and binding sites

ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · 6 copies · chains A, B, C, D, E, F, G
MG · Magnesium ion · metal · 6 copies · chains B, C, D, E, F, G

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7MCS · Cryo-electron microscopy structure of TnsC(1-503)A225V bound to DNA · the same entry in another collection · chain I against I, TM-score 1.00
P05846 · AlphaFold monomer V2.0 prediction for transposon TN7 transposition protein tnsc (P05846) · a predicted model of the same protein · chain G against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05846
Elsewhere: RCSB PDB 7MCS · PDBe 7MCS · UniProt P05846

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