MolNFT v1 · #181946 · protein
Factor xia (pichia pastoris; C500S [C122S]) in complex with the inhibitor milvexian (bms-986177), iupac NAME:(6R,10S)-10-{4-[5- chloro-2-(4-chloro-1H-1,2,3-triazol-1-YL)PHENYL]-6- oxopyrimidin- 1(6H)-yl}-1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-15,11- (METHENO)PYRAZOLO[4,3-B][1,7]DIAZACYCLOTETRADECIN-5(6H)-one
7MBO: “Factor xia (pichia pastoris; C500S [C122S]) in complex with the inhibitor milvexian (bms-986177), iupac…”. X-ray diffraction, 2 ligands (YXG, NAG). MolNFT v1 #181946 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7MBO
- Type
- protein
- Length
- 237 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03951
- Ligands
- YXG, NAG
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 237 | — | P03951 |
Ligands and binding sites
- YXG · Milvexian · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7MBO · FACTOR XIA (PICHIA PASTORIS; C500S [C122S]) IN COMPLEX WITH THE INHIBITOR Milvexian… · the same entry in another collection · chain A against A, TM-score 1.00
- P03951 · AlphaFold monomer V2.0 prediction for coagulation factor XI (P03951) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03951
- Elsewhere: RCSB PDB 7MBO · PDBe 7MBO · UniProt P03951
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