MolNFT v1 · #181698 · protein

NMR structure of GCAP5

7M2M · Guanylate cyclase activator 1A: “NMR structure of GCAP5”. Solution nmr, 2 ligands (MYR, MG), 1 pocket (best druggability 0.85). MolNFT v1 #181698 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7M2M
Type: protein
Length: 182 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Guanylate cyclase activator 1A
UniProt: Q5MAC8
Ligands: MYR, MG
Pockets: 1 · best druggability 0.85

Structure

solution nmr · 1 distinct chain · 57% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Guanylate cyclase activator 1A	protein	182	57% helix, 3% strand	Q5MAC8

Ligands and binding sites

MYR · Myristic acid · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	869	0.85	0.87	90	MYR

Modifications

Observed in the structure: 1 lipid (myristoylation).

Compared structures

7M2M · NMR Structure of GCAP5 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5MAC8
Elsewhere: RCSB PDB 7M2M · PDBe 7M2M · UniProt Q5MAC8

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