MolNFT v1 · #181648 · protein
TVV2 capsid protein
7M12: “TVV2 capsid protein”. Electron microscopy, 20 pockets (best druggability 0.76). MolNFT v1 #181648 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7M12
- Type
- protein
- Length
- 1,329 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein
- UniProt
- Q9JE95
- Pockets
- 20 · best druggability 0.76
Structure
electron microscopy · 2 distinct chains · 29% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Capsid protein | protein | 665 | 28% helix, 13% strand | Q9JE95 |
| A | Capsid protein | protein | 664 | 29% helix, 14% strand | Q9JE95 |
Pockets
20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1013 | 0.76 | 0.78 | 96 | empty |
| 2 | 57 | 0.71 | 0.98 | 24 | empty |
| 3 | 73 | 0.69 | 0.95 | 20 | empty |
| 4 | 443 | 0.67 | 0.79 | 43 | empty |
| 5 | 245 | 0.63 | 0.82 | 31 | empty |
Interfaces
1 interface between chains.
- B–A · 1592 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 7M12 · TVV2 capsid protein · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9JE95
- Elsewhere: RCSB PDB 7M12 · PDBe 7M12 · UniProt Q9JE95
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