MolNFT v1 · #181632 · protein
HPK1 in complex with compound 1
7M0L: “HPK1 in complex with compound 1”. X-ray diffraction, 1 ligand (YK4). MolNFT v1 #181632 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7M0L
- Type
- protein
- Length
- 1,152 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q92918
- Ligands
- YK4
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | — | protein | 289 | — | Q92918 |
| B | — | protein | 285 | — | Q92918 |
| C | — | protein | 289 | — | Q92918 |
Ligands and binding sites
- YK4 · 4-(2-bromoanilino)-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide · ligand · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7M0L · HPK1 in complex with compound 1 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92918
- Elsewhere: RCSB PDB 7M0L · PDBe 7M0L · UniProt Q92918
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