MolNFT v1 · #181602 · protein
Crystal structure of the BCL6 btb domain in complex with oicr-10256
7LZR: “Crystal structure of the BCL6 btb domain in complex with oicr-10256”. X-ray diffraction, 3 ligands (YJJ, SO4, CL). MolNFT v1 #181602 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LZR
- Type
- protein
- Length
- 490 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P41182
- Ligands
- YJJ, SO4, CL
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 123 | — | P41182 |
| B | — | protein | 123 | — | P41182 |
| C, D | — | protein | 122 | — | P41182 |
Ligands and binding sites
- YJJ · N-[5-chloro-2-(morpholin-4-yl)pyridin-4-yl]-2-[5-(3-cyano-4-hydroxy-5-methylphenyl)-3-methyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetamide · ligand · 4 copies · chains A, B, C, D
- SO4 · Sulfate ion · ion · 5 copies · chains A, B, C, D
- CL · Chloride ion · ion · 5 copies · chains A, B, C, D
- GOL · Glycerol · additive · 3 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7LZR · Crystal structure of the BCL6 BTB domain in complex with OICR-10256 · the same entry in another collection · chain D against D, TM-score 1.00
- P41182 · AlphaFold monomer V2.0 prediction for B-cell lymphoma 6 protein (P41182) · a predicted model of the same protein · chain C against A, TM-score 0.32
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41182
- Elsewhere: RCSB PDB 7LZR · PDBe 7LZR · UniProt P41182
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