MolNFT v1 · #18160 · protein
Methionyl-tRNA synthetase from escherichia COLI complexed with methionine and adenosine
1PG2: “Methionyl-tRNA synthetase from escherichia COLI complexed with methionine and adenosine”. X-ray diffraction, 2 ligands (ADN, MET), 1 pocket (best druggability 0.61). MolNFT v1 #18160 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1PG2
- Type
- protein
- Length
- 488 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methionyl-tRNA synthetase
- EC
- 6.1.1.10
- UniProt
- P00959
- Ligands
- ADN, MET
- Pockets
- 1 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 56% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methionyl-tRNA synthetase (EC 6.1.1.10) | protein | 488 | 56% helix, 14% strand | P00959 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 298 | 0.61 | 0.79 | 35 | ADN, MET |
Compared structures
- 1PG2 · Methionyl-tRNA synthetase from escherichia COLI complexed with methionine and adenosine · the same entry in another collection · chain A against A, TM-score 1.00
- P00959 · AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (P00959) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00959
- Elsewhere: RCSB PDB 1PG2 · PDBe 1PG2 · UniProt P00959
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