MolNFT v1 · #181462 · protein
Cryptococcus neoformans gar synthetase
7LVO · Phosphoribosyl-glycinamide (gar) synthetase: “Cryptococcus neoformans gar synthetase”. X-ray diffraction, 2 pockets (best druggability 0.69). MolNFT v1 #181462 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LVO
- Type
- protein
- Length
- 435 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoribosyl-glycinamide (gar) synthetase
- EC
- 6.3.3.1, 6.3.4.13
- UniProt
- J9VYP5
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoribosyl-glycinamide (gar) synthetase (EC 6.3.3.1, 6.3.4.13) | protein | 435 | 31% helix, 28% strand | J9VYP5 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 691 | 0.69 | 0.77 | 74 | EDO |
| 2 | 74 | 0.32 | 0.74 | 16 | empty |
Compared structures
- 7LVO · Cryptococcus neoformans GAR synthetase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt J9VYP5
- Elsewhere: RCSB PDB 7LVO · PDBe 7LVO · UniProt J9VYP5
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