MolNFT v1 · #181458 · protein
CASP8 isoform G ded domain
7LVJ · Isoform 9 of caspase-8: “CASP8 isoform G ded domain”. X-ray diffraction, 2 pockets (best druggability 0.40). MolNFT v1 #181458 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LVJ
- Type
- protein
- Length
- 185 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Isoform 9 of caspase-8
- EC
- 3.4.22.61
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 64% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isoform 9 of caspase-8 (EC 3.4.22.61) | protein | 185 | 64% helix, 2% strand | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 129 | 0.40 | 0.75 | 24 | empty |
| 2 | 82 | 0.36 | 0.76 | 14 | empty |
Compared structures
- 7LVJ · CASP8 isoform G DED domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7LVJ · PDBe 7LVJ
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