MolNFT v1 · #181373 · protein

HSP90A N-terminal inhibitor

7LT0: “HSP90A N-terminal inhibitor”. X-ray diffraction, 1 ligand (ONJ). MolNFT v1 #181373 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7LT0
Type: protein
Length: 208 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P07900
Ligands: ONJ

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	208	—	P07900

Ligands and binding sites

ONJ · (1,3-dihydro-2H-isoindol-2-yl){3-[(3,4-dimethylphenyl) sulfanyl]-4-hydroxyphenyl}methanone · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7LT0 · Hsp90a N-terminal inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
P07900 · AlphaFold monomer V2.0 prediction for heat shock protein HSP 90-alpha (P07900) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07900
Elsewhere: RCSB PDB 7LT0 · PDBe 7LT0 · UniProt P07900

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