MolNFT v1 · #181285 · protein

Cryo-EM structure of omcz nanowire from geobacter sulfurreducens

7LQ5 · Cytochrome C: “Cryo-EM structure of omcz nanowire from geobacter sulfurreducens”. Electron microscopy, 1 ligand (HEC), 5 pockets (best druggability 0.88). MolNFT v1 #181285 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 7LQ5
Type: protein
Length: 774 residues
Chains: 3
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytochrome C
UniProt: Q74BG5
Ligands: HEC
Pockets: 5 · best druggability 0.88

Structure

electron microscopy · 1 distinct chain · 13% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Cytochrome C	protein	258	13% helix, 9% strand	Q74BG5

Ligands and binding sites

HEC · Heme C · ligand · 24 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	882	0.88	0.90	112	HEC
2	880	0.88	0.90	111	HEC
3	557	0.84	0.90	70	HEC
4	142	0.64	0.87	26	HEC
5	55	0.53	0.88	13	empty

Interfaces

2 interfaces between chains.

A–B · 712 Å² buried · 3 hydrogen bonds · protein-protein
B–C · 704 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 48 cofactor (heme c attachment).

Compared structures

7LQ5 · Cryo-EM structure of OmcZ nanowire from Geobacter sulfurreducens · the same entry in another collection · chain C against C, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q74BG5
Elsewhere: RCSB PDB 7LQ5 · PDBe 7LQ5 · UniProt Q74BG5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.