MolNFT v1 · #181086 · RNA

Cryo-EM structure of the B dene construct complexed with a 28-mer POLY(A)

7LJY: “Cryo-EM structure of the B dene construct complexed with a 28-mer POLY(A)”. Electron microscopy, 2 pockets (best druggability 0.69). MolNFT v1 #181086 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7LJY
Type: RNA
Length: 101 nucleotides
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: B dene construct; POLY(A)
Pockets: 2 · best druggability 0.69

Structure

electron microscopy · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	B dene construct	rna	76	—	—
A	POLY(A)	rna	25	—	—

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1012	0.69	0.75	55	empty
2	114	0.47	0.80	14	empty

Interfaces

1 interface between chains.

B–A · 1863 Å² buried · 126 hydrogen bonds · nucleic-nucleic

Compared structures

7LJY · Cryo-EM structure of the B dENE construct complexed with a 28-mer poly(A) · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7LJY · PDBe 7LJY

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