MolNFT v1 · #18106 · protein

Amide RECEPTOR/NEGATIVE regulator of the amidase operon of pseudomonas aeruginosa (amic) complexed with acetamide

1PEA: “Amide RECEPTOR/NEGATIVE regulator of the amidase operon of pseudomonas aeruginosa (amic) complexed with…”. X-ray diffraction, 1 ligand (ACM), 1 pocket (best druggability 0.27). MolNFT v1 #18106 on GenesisL1: 3D structure, binding…

PDB: 1PEA
Type: protein
Length: 368 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Amidase operon
UniProt: P27017
Ligands: ACM
Pockets: 1 · best druggability 0.27

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Amidase operon	protein	368	41% helix, 20% strand	P27017

Ligands and binding sites

ACM · Acetamide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.27	0.73	18	empty

Compared structures

1PEA · Amide RECEPTOR/NEGATIVE regulator of the amidase operon of pseudomonas aeruginosa (amic)… · the same entry in another collection · chain A against A, TM-score 1.00
P27017 · AlphaFold monomer V2.0 prediction for aliphatic amidase expression- regulating protein… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27017
Elsewhere: RCSB PDB 1PEA · PDBe 1PEA · UniProt P27017

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