MolNFT v1 · #181032 · protein

The structure of the insect olfactory receptor OR5 from machilis hrabei

7LIC · MHOR5: “The structure of the insect olfactory receptor OR5 from machilis hrabei”. Electron microscopy, 20 pockets (best druggability 0.80). MolNFT v1 #181032 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7LIC
Type: protein
Length: 1,508 residues
Chains: 4
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: MHOR5
Pockets: 20 · best druggability 0.80

Structure

electron microscopy · 1 distinct chain · 78% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	MHOR5	protein	377	78% helix, 1% strand	—

Pockets

20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	976	0.80	0.81	91	empty
2	324	0.75	0.86	45	empty
3	565	0.65	0.76	51	empty
4	110	0.65	0.89	19	empty
5	109	0.64	0.88	20	empty

Interfaces

6 interfaces between chains.

A–B · 1301 Å² buried · 5 hydrogen bonds · protein-protein
C–D · 1287 Å² buried · 4 hydrogen bonds · protein-protein
A–D · 1284 Å² buried · 5 hydrogen bonds · protein-protein
B–C · 1257 Å² buried · 4 hydrogen bonds · protein-protein
A–C · 26 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

7LIC · The structure of the insect olfactory receptor OR5 from Machilis hrabei · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7LIC · PDBe 7LIC

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