MolNFT v1 · #180902 · protein
Crystal structure of the second bromodomain (BD2) of human brdt bound to volasertib
7LEJ: “Crystal structure of the second bromodomain (BD2) of human brdt bound to volasertib”. X-ray diffraction, 1 ligand (IBI). MolNFT v1 #180902 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LEJ
- Type
- protein
- Length
- 121 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q58F21
- Ligands
- IBI
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 121 | — | Q58F21 |
Ligands and binding sites
- IBI · N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7LEJ · Crystal structure of the second bromodomain (BD2) of human BRDT bound to Volasertib · the same entry in another collection · chain A against A, TM-score 1.00
- Q58F21 · AlphaFold monomer V2.0 prediction for bromodomain testis-specific protein (Q58F21) · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q58F21
- Elsewhere: RCSB PDB 7LEJ · PDBe 7LEJ · UniProt Q58F21
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