MolNFT v1 · #180829 · protein + DNA
Helitron transposase bound to lts
7LCC · Helraiser K1068Q: “Helitron transposase bound to lts”. Electron microscopy, 1 ligand (ZN), 20 pockets (best druggability 0.89). MolNFT v1 #180829 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LCC
- Type
- protein + DNA
- Length
- 1,386 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Helraiser K1068Q; Lts
- Ligands
- ZN
- Pockets
- 20 · best druggability 0.89
Structure
electron microscopy · 2 distinct chains · 36% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Helraiser K1068Q | protein | 1369 | 36% helix, 17% strand | — |
| B | Lts | dna | 17 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 982 | 0.89 | 0.91 | 108 | empty |
| 2 | 627 | 0.82 | 0.87 | 82 | empty |
| 3 | 482 | 0.76 | 0.84 | 48 | empty |
| 4 | 142 | 0.70 | 0.90 | 28 | empty |
| 5 | 111 | 0.70 | 0.92 | 25 | empty |
Interfaces
1 interface between chains.
- A–B · 1977 Ų buried · 27 hydrogen bonds · protein-nucleic
Compared structures
- 7LCC · Helitron transposase bound to LTS · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7LCC · PDBe 7LCC
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.