MolNFT v1 · #180801 · protein
Crystal structure of octaprenyl diphosphate synthase from stenotrophomonas maltophilia
7LBJ · Geranyltranstransferase: “Crystal structure of octaprenyl diphosphate synthase from stenotrophomonas maltophilia”. X-ray diffraction, 1 ligand (CL), 6 pockets (best druggability 0.69). MolNFT v1 #180801 on GenesisL1: 3D structure…
- PDB
- 7LBJ
- Type
- protein
- Length
- 553 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Geranyltranstransferase
- EC
- 2.5.1.10
- UniProt
- B2FP37
- Ligands
- CL
- Pockets
- 6 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 73% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Geranyltranstransferase (EC 2.5.1.10) | protein | 278 | 72% helix, 1% strand | B2FP37 |
| B | Geranyltranstransferase (EC 2.5.1.10) | protein | 275 | 75% helix, 1% strand | B2FP37 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 451 | 0.69 | 0.81 | 48 | empty |
| 2 | 494 | 0.65 | 0.78 | 48 | empty |
| 3 | 75 | 0.41 | 0.80 | 17 | empty |
| 4 | 51 | 0.40 | 0.82 | 13 | empty |
| 5 | 75 | 0.36 | 0.77 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1697 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 7LBJ · Crystal structure of octaprenyl diphosphate synthase from Stenotrophomonas maltophilia · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2FP37
- Elsewhere: RCSB PDB 7LBJ · PDBe 7LBJ · UniProt B2FP37
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.