MolNFT v1 · #180414 · protein

Crystal structure of human bccip beta (NATIVE1)

7KYQ · BRCA2 and CDKN1A-interacting protein: “Crystal structure of human bccip beta (NATIVE1)”. X-ray diffraction, 2 pockets (best druggability 0.39). MolNFT v1 #180414 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7KYQ
Type: protein
Length: 230 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BRCA2 and CDKN1A-interacting protein
EC: 2.-.-.-
UniProt: Q9P287
Pockets: 2 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	BRCA2 and CDKN1A-interacting protein (EC 2.-.-.-)	protein	230	39% helix, 23% strand	Q9P287

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.39	0.78	19	empty
2	67	0.30	0.73	15	empty

Compared structures

7KYQ · Crystal structure of human BCCIP beta (Native1) · the same entry in another collection · chain A against A, TM-score 1.00
Q9P287 · AlphaFold monomer V2.0 prediction for BRCA2 and CDKN1A-interacting protein (Q9P287) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9P287
Elsewhere: RCSB PDB 7KYQ · PDBe 7KYQ · UniProt Q9P287

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