MolNFT v1 · #18032 · protein

SEC7 domain of the exchange factor arno

1PBV: “SEC7 domain of the exchange factor arno”. X-ray diffraction, 1 pocket (best druggability 0.31). MolNFT v1 #18032 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1PBV
Type: protein
Length: 195 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Arno
UniProt: Q99418
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 66% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Arno	protein	195	66% helix, 1% strand	Q99418

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.31	0.76	12	empty

Compared structures

1PBV · SEC7 domain of the exchange factor arno · the same entry in another collection · chain A against A, TM-score 1.00
Q99418 · AlphaFold monomer V2.0 prediction for cytohesin-2 (Q99418) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99418
Elsewhere: RCSB PDB 1PBV · PDBe 1PBV · UniProt Q99418

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