MolNFT v1 · #18030 · protein
The crystal structure of TM1154, oxidoreductase, SOL/DEVB family from thermotoga maritima
1PBT · 6-phosphogluconolactonase: “The crystal structure of TM1154, oxidoreductase, SOL/DEVB family from thermotoga maritima”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.53). MolNFT v1 #18030 on GenesisL1: 3D…
- PDB
- 1PBT
- Type
- protein
- Length
- 220 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 6-phosphogluconolactonase
- EC
- 3.1.1.31
- UniProt
- Q9X0N8
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 6-phosphogluconolactonase (EC 3.1.1.31) | protein | 220 | 37% helix, 23% strand | Q9X0N8 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
- EDO · 1,2-ethanediol · additive · chains A
- FMT · Formic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 190 | 0.53 | 0.79 | 29 | SO4 |
| 2 | 50 | 0.38 | 0.80 | 12 | empty |
Modifications
Observed in the structure: 3 modified (engineered).
Compared structures
- 1PBT · The crystal structure of TM1154, oxidoreductase, sol/devB family from Thermotoga maritima · the same entry in another collection · chain A against A, TM-score 1.00
- Q9X0N8 · AlphaFold monomer V2.0 prediction for 6-phosphogluconolactonase (Q9X0N8) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X0N8
- Elsewhere: RCSB PDB 1PBT · PDBe 1PBT · UniProt Q9X0N8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.