MolNFT v1 · #180293 · protein
Cyro-EM structure of human glycine receptor ALPHA2-beta heteromer, strychnine bound state
7KUY: “Cyro-EM structure of human glycine receptor ALPHA2-beta heteromer, strychnine bound state”. Electron microscopy, 2 ligands (SY9, NAG). MolNFT v1 #180293 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KUY
- Type
- protein
- Length
- 1,694 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P23416, P48167, P42212
- Ligands
- SY9, NAG
Structure
electron microscopy · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 339 | — | P23416 |
| E | — | protein | 338 | — | P48167, P42212 |
Ligands and binding sites
- SY9 · Strychnine · ligand · 5 copies · chains A, E, B, C, D
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains A, B, C, D, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KUY · Cyro-EM structure of human Glycine Receptor alpha2-beta heteromer, strychnine bound state · the same entry in another collection · chain A against A, TM-score 1.00
- P23416 · AlphaFold monomer V2.0 prediction for glycine receptor subunit alpha-2 (P23416) · a predicted model of the same protein · chain C against A, TM-score 0.92
- P48167 · AlphaFold monomer V2.0 prediction for glycine receptor subunit beta (P48167) · a predicted model of the same protein · chain E against A, TM-score 0.92
- P42212 · AlphaFold monomer V2.0 prediction for green fluorescent protein (P42212) · a predicted model of the same protein · chain E against A, TM-score 0.22
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23416
- Every structure of UniProt P48167
- Every structure of UniProt P42212
- Elsewhere: RCSB PDB 7KUY · PDBe 7KUY · UniProt P23416 · UniProt P48167 · UniProt P42212
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