MolNFT v1 · #18019 · protein
Crystal structure of human recombinant procathepsin B at 3.2 ångström resolution
1PBH: “Crystal structure of human recombinant procathepsin B at 3.2 ångström resolution”. X-ray diffraction, 1 pocket (best druggability 0.27). MolNFT v1 #18019 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1PBH
- Type
- protein
- Length
- 317 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Procathepsin B
- EC
- 3.4.22.1
- UniProt
- P07858
- Pockets
- 1 · best druggability 0.27
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Procathepsin B (EC 3.4.22.1) | protein | 317 | 26% helix, 22% strand | P07858 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.27 | 0.73 | 20 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 1PBH · Crystal structure of human recombinant procathepsin B at 3.2 ångström resolution · the same entry in another collection · chain A against A, TM-score 1.00
- P07858 · AlphaFold monomer V2.0 prediction for cathepsin B (P07858) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07858
- Elsewhere: RCSB PDB 1PBH · PDBe 1PBH · UniProt P07858
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