MolNFT v1 · #180109 · protein

SARS-cov-2 main protease in mature form

7KPH · 3C-like proteinase: “SARS-cov-2 main protease in mature form”. X-ray diffraction, 3 pockets (best druggability 0.51). MolNFT v1 #180109 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7KPH
Type: protein
Length: 306 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 3C-like proteinase
EC: 3.4.22.69
UniProt: P0DTD1
Pockets: 3 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	3C-like proteinase (EC 3.4.22.69)	protein	306	26% helix, 29% strand	P0DTD1

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	200	0.51	0.77	25	empty
2	64	0.51	0.86	17	empty
3	127	0.42	0.75	29	empty

Compared structures

7KPH · SARS-CoV-2 Main Protease in mature form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0DTD1
Elsewhere: RCSB PDB 7KPH · PDBe 7KPH · UniProt P0DTD1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.