MolNFT v1 · #180103 · protein
Mtnf-alpha HTNFR1 complex
7KPB: “Mtnf-alpha HTNFR1 complex”. X-ray diffraction, 2 ligands (D84, NAG). MolNFT v1 #180103 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KPB
- Type
- protein
- Length
- 1,141 residues
- Chains
- 7
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P01375, P19438
- Ligands
- D84, NAG
Structure
x-ray diffraction · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 153 | — | P01375 |
| B | — | protein | 143 | — | P01375 |
| C | — | protein | 138 | — | P01375 |
| F | — | protein | 141 | — | P19438 |
| E | — | protein | 141 | — | P19438 |
| L | — | protein | 213 | — | — |
| H | — | protein | 212 | — | — |
Ligands and binding sites
- D84 · 5-(1-{[2-(difluoromethoxy)phenyl]methyl}-2-{[3-(2-oxopyrrolidin-1-yl)phenoxy]methyl}-1H-benzimidazol-6-yl)pyridin-2(1H)-one · ligand · chains A, B, C
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains E
- GOL · Glycerol · additive · 9 copies · chains A, B, F, C, E, L
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KPB · Human TNF-alpha TNFR1 complex bound to conformationally selective antibody · the same entry in another collection · chain H against H, TM-score 1.00
- P19438 · AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member… · a predicted model of the same protein · chain F against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01375
- Every structure of UniProt P19438
- Elsewhere: RCSB PDB 7KPB · PDBe 7KPB · UniProt P01375 · UniProt P19438
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