MolNFT v1 · #179916 · protein + RNA
Keops tRNA modifying sub-complex of archaeal CGI121 and tRNA
7KJT · RNA (70-mer): “Keops tRNA modifying sub-complex of archaeal CGI121 and tRNA”. X-ray diffraction, 4 pockets (best druggability 0.63). MolNFT v1 #179916 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KJT
- Type
- protein + RNA
- Length
- 215 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA (70-mer); Regulatory protein CGI121
- UniProt
- Q57646
- Pockets
- 4 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA (70-mer) | rna | 70 | — | — |
| H | Regulatory protein CGI121 | protein | 145 | 53% helix, 16% strand | Q57646 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 484 | 0.63 | 0.77 | 25 | empty |
| 2 | 175 | 0.43 | 0.74 | 22 | empty |
| 3 | 80 | 0.42 | 0.79 | 15 | empty |
| 4 | 102 | 0.31 | 0.72 | 12 | empty |
Interfaces
1 interface between chains.
- A–H · 596 Ų buried · 11 hydrogen bonds · protein-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q57646
- Elsewhere: RCSB PDB 7KJT · PDBe 7KJT · UniProt Q57646
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