MolNFT v1 · #17982 · protein
Crystal structure of glutathione-S-transferase from plasmodium falciparum
1PA3 · Glutathione S-transferase, putative: “Crystal structure of glutathione-S-transferase from plasmodium falciparum”. X-ray diffraction, 3 pockets (best druggability 0.65). MolNFT v1 #17982 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1PA3
- Type
- protein
- Length
- 392 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutathione S-transferase, putative
- UniProt
- Q95V54
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 61% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Glutathione S-transferase, putative | protein | 196 | 61% helix, 9% strand | Q95V54 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.65 | 0.92 | 17 | empty |
| 2 | 327 | 0.54 | 0.74 | 47 | empty |
| 3 | 106 | 0.41 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1189 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 1PA3 · Crystal Structure of Glutathione-S-transferase from Plasmodium falciparum · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q95V54
- Elsewhere: RCSB PDB 1PA3 · PDBe 1PA3 · UniProt Q95V54
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