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MolNFT v1 · #179767 · protein

Ebola virus gp (mucin deleted, makona strain) bound to antibody Fab ebov-437

7KFH: “Ebola virus gp (mucin deleted, makona strain) bound to antibody Fab ebov-437”. Electron microscopy, 3 ligands (NAG, MAN, BMA). MolNFT v1 #179767 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7KFH
Type
protein
Length
1,695 residues
Chains
12
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0A1C4HDV6, A0A0E3XK95
Ligands
NAG, MAN, BMA

Structure

electron microscopy · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C—protein229—A0A1C4HDV6
J, K, L—protein108——
D, E, F—protein95—A0A0E3XK95
G, H, I—protein133——

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 21 copies · chains A, D, E, B, F, C, G, H, I
  • MAN · alpha-D-mannopyranose · sugar · 6 copies · chains E, F, D
  • BMA · beta-D-mannopyranose · sugar · 3 copies

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7KFH · Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437 · the same entry in another collection · chain A against A, TM-score 1.00

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