MolNFT v1 · #17976 · RNA

The crystal structure of the 50S large ribosomal subunit from deinococcus radiodurans complexed with telithromycin ketolide antibiotic

1P9X · 23S ribosomal RNA: “The crystal structure of the 50S large ribosomal subunit from deinococcus radiodurans complexed with…”. X-ray diffraction, 1 ligand (TEL), 20 pockets (best druggability 0.84). MolNFT v1 #17976 on GenesisL1: 3D…

PDB: 1P9X
Type: RNA
Length: 2,738 nucleotides
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 23S ribosomal RNA
Ligands: TEL
Pockets: 20 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
0	23S ribosomal RNA	rna	2738	—	—

Ligands and binding sites

TEL · Telithromycin · ligand · chains 0

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	858	0.84	0.88	64	empty
2	842	0.84	0.87	74	empty
3	1092	0.83	0.85	67	empty
4	850	0.83	0.86	62	empty
5	651	0.81	0.87	56	empty

Compared structures

1P9X · The crystal structure of the 50S large ribosomal subunit from deinococcus radiodurans… · the same entry in another collection · chain 0 against 0, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1P9X · PDBe 1P9X

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