MolNFT v1 · #179368 · protein

SARS-cov-2 envelope protein transmembrane domain: pentameric structure determined by solid-state NMR

7K3G · Envelope small membrane protein: “SARS-cov-2 envelope protein transmembrane domain: pentameric structure determined by solid-state NMR”. Solid-state nmr, 2 pockets (best druggability 0.81). MolNFT v1 #179368 on GenesisL1: 3D…

PDB: 7K3G
Type: protein
Length: 155 residues
Chains: 5
Method: solid-state nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Envelope small membrane protein
UniProt: P0DTC4
Pockets: 2 · best druggability 0.81

Structure

solid-state nmr · 1 distinct chain · 84% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E	Envelope small membrane protein	protein	31	84% helix, 0% strand	P0DTC4

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	695	0.81	0.84	63	empty
2	240	0.59	0.79	28	empty

Interfaces

5 interfaces between chains.

B–C · 610 Å² buried · 2 hydrogen bonds · protein-protein
C–D · 609 Å² buried · 2 hydrogen bonds · protein-protein
D–E · 609 Å² buried · 2 hydrogen bonds · protein-protein
A–E · 608 Å² buried · 2 hydrogen bonds · protein-protein
A–B · 604 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

7K3G · SARS-CoV-2 Envelope Protein Transmembrane Domain: Pentameric Structure Determined by… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0DTC4
Elsewhere: RCSB PDB 7K3G · PDBe 7K3G · UniProt P0DTC4

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