MolNFT v1 · #179318 · protein
Partial open state of mycobacterium tuberculosis zinc metalloprotease 1
7K1V: “Partial open state of mycobacterium tuberculosis zinc metalloprotease 1”. Electron microscopy, 16 pockets (best druggability 0.78). MolNFT v1 #179318 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7K1V
- Type
- protein
- Length
- 626 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Zinc metalloprotease
- EC
- 3.4.24.-
- UniProt
- A0A045IRG4
- Pockets
- 16 · best druggability 0.78
Structure
electron microscopy · 1 distinct chain · 50% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zinc metalloprotease (EC 3.4.24.-) | protein | 626 | 50% helix, 4% strand | A0A045IRG4 |
Pockets
16 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 867 | 0.78 | 0.81 | 76 | empty |
| 2 | 103 | 0.76 | 0.95 | 31 | empty |
| 3 | 472 | 0.75 | 0.83 | 50 | empty |
| 4 | 179 | 0.74 | 0.90 | 37 | empty |
| 5 | 172 | 0.73 | 0.90 | 33 | empty |
Compared structures
- 7K1V · Partial open state of Mycobacterium tuberculosis zinc metalloprotease 1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A045IRG4
- Elsewhere: RCSB PDB 7K1V · PDBe 7K1V · UniProt A0A045IRG4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.