MolNFT v1 · #179258 · protein
Crystal structure of the tandem bromodomain (BD1 and BD2) of human TAF1 bound to atr kinase inhibitor AZD6738
7K03: “Crystal structure of the tandem bromodomain (BD1 and BD2) of human TAF1 bound to atr kinase inhibitor AZD6738”. X-ray diffraction, 1 ligand (VJM). MolNFT v1 #179258 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7K03
- Type
- protein
- Length
- 248 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P21675
- Ligands
- VJM
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 248 | — | P21675 |
Ligands and binding sites
- VJM · 4-(4-{1-[(R)-amino(hydroxy)methyl-lambda~4~-sulfanyl]cyclopropyl}-6-[(3R)-3-methylmorpholin-4-yl]pyrimidin-2-yl)-1H-pyrrolo[2,3-b]pyridine · ligand · chains A
- EDO · 1,2-ethanediol · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7K03 · Crystal structure of the tandem bromodomain (BD1 and BD2) of human TAF1 bound to ATR… · the same entry in another collection · chain A against A, TM-score 1.00
- P21675 · AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 1… · a predicted model of the same protein · chain A against A, TM-score 0.51
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21675
- Elsewhere: RCSB PDB 7K03 · PDBe 7K03 · UniProt P21675
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