MolNFT v1 · #179171 · protein

Structural model for fe-containing human acireductone dioxygenase

7JXG · 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase: “Structural model for fe-containing human acireductone dioxygenase”. Solution nmr, 1 ligand (FE2), 1 pocket (best druggability 0.67). MolNFT v1 #179171 on GenesisL1: 3D…

PDB: 7JXG
Type: protein
Length: 178 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
EC: 1.13.11.54
UniProt: Q9BV57
Ligands: FE2
Pockets: 1 · best druggability 0.67

Structure

solution nmr · 1 distinct chain · 28% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)	protein	178	28% helix, 29% strand	Q9BV57

Ligands and binding sites

FE2 · Fe (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	205	0.67	0.85	39	empty

Compared structures

7JXG · Structural model for Fe-containing human acireductone dioxygenase · the same entry in another collection · chain A against A, TM-score 1.00
Q9BV57 · AlphaFold monomer V2.0 prediction for 1,2-dihydroxy-3-keto-5-methylthiopentene… · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BV57
Elsewhere: RCSB PDB 7JXG · PDBe 7JXG · UniProt Q9BV57

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