MolNFT v1 · #179131 · protein

Crystal structure of drosophila nibbler exo domain

7JW6 · Exonuclease mut-7 homolog: “Crystal structure of drosophila nibbler exo domain”. X-ray diffraction, 2 pockets (best druggability 0.56). MolNFT v1 #179131 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7JW6
Type: protein
Length: 226 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Exonuclease mut-7 homolog
EC: 3.1.-.-
UniProt: Q9VIF1
Pockets: 2 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Exonuclease mut-7 homolog (EC 3.1.-.-)	protein	226	41% helix, 17% strand	Q9VIF1

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	254	0.56	0.77	24	empty
2	100	0.38	0.76	18	empty

Compared structures

7JW6 · Crystal structure of Drosophila Nibbler EXO domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9VIF1 · AlphaFold monomer V2.0 prediction for exonuclease mut-7 homolog (Q9VIF1) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9VIF1
Elsewhere: RCSB PDB 7JW6 · PDBe 7JW6 · UniProt Q9VIF1

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