MolNFT v1 · #179042 · protein
Crystal structure of rar-related orphan receptor C (nhis-RORGT(244- 487)-L6-SRC1(6T78-692) in complex with a tricyclic sulfone rorgt inverse agonist
7JTM: “Crystal structure of rar-related orphan receptor C (nhis-RORGT(244- 487)-L6-SRC1(6T78-692) in complex with a…”. X-ray diffraction, 1 ligand (VK7). MolNFT v1 #179042 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7JTM
- Type
- protein
- Length
- 253 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P51449
- Ligands
- VK7
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 253 | — | P51449 |
Ligands and binding sites
- VK7 · Trans-4-[(3ar,9br)-8-cyano-9B-[(4-fluorophenyl) sulfonyl]-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1, 2,3A,4,5,9B-hexahydro-3H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7JTM · Crystal structure of rar-related orphan receptor C (nhis-RORGT(244-487)-L6-SRC1(6T78-692)… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51449
- Elsewhere: RCSB PDB 7JTM · PDBe 7JTM · UniProt P51449
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