MolNFT v1 · #179020 · protein

Crystal structure of SARS-cov-2 3CL in apo form

7JST · 3C-like proteinase: “Crystal structure of SARS-cov-2 3CL in apo form”. X-ray diffraction, 1 ligand (PO4), 2 pockets (best druggability 0.46). MolNFT v1 #179020 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7JST
Type: protein
Length: 301 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 3C-like proteinase
EC: 3.4.22.69
UniProt: P0DTD1
Ligands: PO4
Pockets: 2 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	3C-like proteinase (EC 3.4.22.69)	protein	301	26% helix, 29% strand	P0DTD1

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	188	0.46	0.75	27	empty
2	63	0.31	0.75	14	empty

Compared structures

7JST · Crystal structure of SARS-CoV-2 3CL in apo form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0DTD1
Elsewhere: RCSB PDB 7JST · PDBe 7JST · UniProt P0DTD1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.