MolNFT v1 · #178798 · protein
Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector xopq (tir domains)
7JLX · Disease resistance protein ROQ1: “Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector xopq (tir domains)”. Electron microscopy, 7 pockets (best druggability 0.77). MolNFT v1 #178798 on GenesisL1…
- PDB
- 7JLX
- Type
- protein
- Length
- 664 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Disease resistance protein ROQ1
- EC
- 3.2.2.6
- UniProt
- A0A290U7C4
- Pockets
- 7 · best druggability 0.77
Structure
electron microscopy · 1 distinct chain · 49% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, C, A, D | Disease resistance protein ROQ1 (EC 3.2.2.6) | protein | 166 | 49% helix, 11% strand | A0A290U7C4 |
Pockets
7 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1149 | 0.77 | 0.79 | 103 | empty |
| 2 | 655 | 0.75 | 0.81 | 77 | empty |
| 3 | 618 | 0.75 | 0.82 | 69 | empty |
| 4 | 864 | 0.74 | 0.78 | 82 | empty |
| 5 | 345 | 0.66 | 0.81 | 54 | empty |
Interfaces
5 interfaces between chains.
- C–A · 204 Ų buried · 0 hydrogen bonds · protein-protein
- B–D · 199 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 166 Ų buried · 2 hydrogen bonds · protein-protein
- A–D · 165 Ų buried · 2 hydrogen bonds · protein-protein
- B–A · 11 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7JLX · Structure of the activated Roq1 resistosome directly recognizing the pathogen effector… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A290U7C4
- Elsewhere: RCSB PDB 7JLX · PDBe 7JLX · UniProt A0A290U7C4
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